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In This Issue of JAMA
Audio Highlights
Abstract Full Text
free access online only has audio
JAMA. 2024;332(2):e2318339. doi:10.1001/jama.2023.18339
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Audio: EEG-Guided Anesthesia and Delirium, Integrating Clinical Trials With Clinical Practice, Depression Review, and more
Original Investigation
Electroencephalography-Guided Anesthesia and Delirium in Older Adults After Cardiac Surgery: The ENGAGES-Canada Randomized Clinical Trial
AlainDeschamps,MD, PhD; ArbiBen Abdallah,PhD; EricJacobsohn,MD, ChB; et al.
Abstract Full Text
JAMA. 2024;332(2):112-123. doi:10.1001/jama.2024.8144
This randomized clinical trial examines whether electroencephalogram -guided anesthesia decreases the incidence of delirium after cardiac surgery among adults 60 years or older.
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Editorial
Anesthesia Dose and Delirium—A Picture Coming Into FocusMilesBerger,MD, PhD; Mark D.Neuman,MD, MSc
JAMA
Association Between Cost Sharing and Naloxone Prescription Dispensing
Kao-PingChua,MD, PhD; Rena M.Conti,PhD; PoojaLagisetty,MD; et al.
Abstract Full Text
JAMA. 2024;332(2):124-132. doi:10.1001/jama.2024.8378
This study evaluates the association between cost sharing and naloxone prescription abandonment (nondispensing of naloxone prescriptions) in commercial insurance and Medicare plans.
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Editorial
Costs and Essential Drug Access—The Case of NaloxoneLeoBeletsky,JD, MPH; Max Jordan NguemeniTiako,MD, MS
JAMA
Mortality and Morbidity in Adults With Rheumatic Heart Disease
GanesanKarthikeyan,DM; MpikoNtsekhe,PhD; ShofiqulIslam,PhD; et al.
Abstract Full Text
has active quiz
JAMA. 2024;332(2):133-140. doi:10.1001/jama.2024.8258
This prospective observational study investigates mortality rates and predictive risk factors for rheumatic heart disease in 24 endemic low- and middle-income countries and evaluates interventions like corrective valve surgery and valvuloplasty.
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Editorial
Rheumatic Heart Disease—A Neglected Tragedy in Young PatientsKumarNarayanan,MD; EloiMarijon,MD, PhD
JAMA Cardiol
Research Letter
Trends in Naloxone Dispensing From Retail Pharmacies in the US
S. MichaelaRikard,PhD; Andrea E.Strahan,PhD; Lyna Z.Schieber,MD, DPhil; et al.
Abstract Full Text
JAMA. 2024;332(2):165-167. doi:10.1001/jama.2024.8323
This cross-sectional study examines trends in naloxone dispensing by US retail pharmacies from 2019 to 2023, including prescriber specialty and product brand.
Trends in Preeclampsia Risk Factors in the US From 2010 to 2021
Mariam K.Ayyash,MD, MSCR; RodneyMcLarenJr,MD; MajidShaman,MD; et al.
Abstract Full Text
JAMA. 2024;332(2):167-169. doi:10.1001/jama.2024.8931
This population-based retrospective study uses data from the National Vital Statistics System to evaluate trends in risk factors for preeclampsia in the US between 2010 and 2021.
Special Communication
Integrating Clinical Trials and Practice
The Integration of Clinical Trials With the Practice of Medicine: Repairing a House Divided
Derek C.Angus,MD, MPH; Alison J.Huang,MD, MAS; Roger J.Lewis,MD, PhD; et al.
Abstract Full Text
has active quiz has audio
JAMA. 2024;332(2):153-162. doi:10.1001/jama.2024.4088
This Special Communication discusses the need for better integration of clinical trials and health care delivery enterprises.
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Audio: Integrating Clinical Trials With the Practice of Medicine
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Editorial
Introducing the JAMA SummitKirstenBibbins-Domingo,PhD, MD, MAS; Derek C.Angus,MD, MPH; HannahPark; Roger J.Lewis,MD, PhD; RohanKhera,MD, MS; JenniferZeis; AnnetteFlanagin,RN, MA; GregoryCurfman,MD
JAMA
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Editor's Note
Integrating Clinical Trials and Practice: A New JAMA Series and Call for PapersGregoryCurfman,MD
JAMA
Viewpoint
Health and the 2024 US Election
Early Pregnancy Loss in an Era of “Wrongful Embryonic Death”
Allen J.Wilcox,MD, PhD; Lisa C.Ikemoto,JD, LLM
Abstract Full Text
JAMA. 2024;332(2):99-100. doi:10.1001/jama.2024.7403
This Viewpoint examines the possible legal consequences of pregnancy loss following the Alabama Supreme Court’s decision to extend personhood to laboratory-conceived embryos.
Upholding Standards for Qualified Bilingual Staff
AdaugoAmobi,MD, MPH
Abstract Full Text
JAMA. 2024;332(2):101-102. doi:10.1001/jama.2024.8896
This Viewpoint discusses ways to ensure the proficiency of bilingual communication among health care staff in patient-clinician encounters, such as language testing and use of professional interpreters.
Integrating Clinical Trials and Practice
Why Should the FDA Focus on Pragmatic Clinical Research?
Ali B.Abbasi,MD; Lesley H.Curtis,PhD; Robert M.Califf,MD
Abstract Full Text
JAMA. 2024;332(2):103-104. doi:10.1001/jama.2024.6227
This Viewpoint from the FDA discusses how pragmatic clinical research—assessment that uses real-world data, often in combination with research data, after initial marketing approval—can help in evaluation of new technologies, benefit research sites in underresourced settings, and better inform regulatory decisions and clinical practice.
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Editor's Note
Integrating Clinical Trials and Practice: A New JAMA Series and Call for PapersGregoryCurfman,MD
JAMA
A Piece of My Mind
The Weight of a Differential
Maren E.Olson,MD, MPH, MEd
Abstract Full Text
JAMA. 2024;332(2):105-106. doi:10.1001/jama.2024.8766
In this narrative medicine essay, when a physician’s mother begins experiencing postmenopausal bleeding, the author wonders what it would be like to hear someone’s signs and symptoms and not automatically begin to build a differential.
Editorial
Anesthesia Dose and Delirium—A Picture Coming Into Focus
MilesBerger,MD, PhD; Mark D.Neuman,MD, MSc
Abstract Full Text
JAMA. 2024;332(2):107-108. doi:10.1001/jama.2023.26819
Costs and Essential Drug Access—The Case of Naloxone
LeoBeletsky,JD, MPH; Max Jordan NguemeniTiako,MD, MS
Abstract Full Text
JAMA. 2024;332(2):109-110. doi:10.1001/jama.2024.7012
Review
Management of Depression in Adults: A Review
Gregory E.Simon,MD, MPH; NathalieMoise,MD, MS; David C.Mohr,PhD
Abstract Full Text
has active quiz has audio
JAMA. 2024;332(2):141-152. doi:10.1001/jama.2024.5756
This narrative review uses data from network meta-analyses and systematic reviews to explore the prevalence, diagnosis, and treatment of major depression in US adults, including specific forms of psychotherapy and more than 20 antidepressant medications.
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Audio: Managing Depression in Adults
JAMA Guide to Statistics and Methods
Test-Negative Study Designs for Evaluating Vaccine Effectiveness
NatalieDean,PhD; Avnika B.Amin,PhD
Abstract Full Text
has active quiz
JAMA. 2024;332(2):163-164. doi:10.1001/jama.2024.5633
This JAMA Guide to Statistics and Methods article explains the test-negative study design, an observational study design routinely used to estimate vaccine effectiveness, and examines its use in a study that estimated the performance of messenger RNA boosters against the Omicron variant.
Editor's Note
Integrating Clinical Trials and Practice
Integrating Clinical Trials and Practice: A New JAMA Series and Call for Papers
GregoryCurfman,MD
Abstract Full Text
free access
JAMA. 2024;332(2):111. doi:10.1001/jama.2024.10266
Poetry and Seeing the Sacred in Medicine
RafaelCampo,MD, MA
Abstract Full Text
JAMA. 2024;332(2):174. doi:10.1001/jama.2024.7221
Medical News & Perspectives
Syphilis Has Surged for Reasons That Go Beyond the Pathogen That Causes It
RitaRubin,MA
Abstract Full Text
has audio
JAMA. 2024;332(2):92-95. doi:10.1001/jama.2024.2978
This Medical News story discusses the multiple factors contributing to the resurgence of syphilis in the US.
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Audio: June 2024 Medical News Summary
Medical News in Brief
AAP Changes Its Breastfeeding Policy for People With HIV in US
EmilyHarris
Abstract Full Text
JAMA. 2024;332(2):96. doi:10.1001/jama.2024.10335
Counting Minutes, Steps Linked With Similar Mortality Reduction
EmilyHarris
Abstract Full Text
JAMA. 2024;332(2):96. doi:10.1001/jama.2024.10336
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Editor's Note
Tracking Physical Activity One Step at a TimeCary P.Gross,MD; Raegan W.Durant,MD, MPH
JAMA Intern Med
Rare Inherited Tumor Syndrome Tied to Nail Condition
EmilyHarris
Abstract Full Text
JAMA. 2024;332(2):96. doi:10.1001/jama.2024.10337
Progestogen May Lower Risk for More Surgery for Endometriosis Pain
EmilyHarris
Abstract Full Text
JAMA. 2024;332(2):96. doi:10.1001/jama.2024.10338
Having Peers With Mental Disorders Might Increase Classmates’ Risk
EmilyHarris
Abstract Full Text
JAMA. 2024;332(2):96-97. doi:10.1001/jama.2024.10339
Fish Oil Pills Associated With Increased Risk of Heart Problems in Healthy People
EmilyHarris
Abstract Full Text
JAMA. 2024;332(2):97. doi:10.1001/jama.2024.10340
Cognitive Impairment Underestimated Among American Indian People
EmilyHarris
Abstract Full Text
JAMA. 2024;332(2):97. doi:10.1001/jama.2024.10341
Early Therapy for Symptomatic COPD, Asthma Improved Quality of Life
EmilyHarris
Abstract Full Text
JAMA. 2024;332(2):97. doi:10.1001/jama.2024.10342
Review Calls for Standardized Long COVID Definition
EmilyHarris
Abstract Full Text
JAMA. 2024;332(2):97. doi:10.1001/jama.2024.10343
Poetry and Medicine
Radiance
RonnieSirmans,ABJ
Abstract Full Text
JAMA. 2024;332(2):174. doi:10.1001/jama.2024.7205
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Editor's Note
Poetry and Seeing the Sacred in MedicineRafaelCampo,MD, MA
JAMA
JAMA Revisited
The Conquest of Yellow Fever
Abstract Full Text
JAMA. 2024;332(2):175. doi:10.1001/jama.2023.18340
JAMA Patient Page
What Is Lynch Syndrome?
KaseyHornbuckle,MD; Cassandra D. L.Fritz,MD, MPHS
Abstract Full Text
free access
JAMA. 2024;332(2):178. doi:10.1001/jama.2024.8552
This JAMA Patient Page describes Lynch syndrome, its risk factors and diagnosis, and its association with colorectal cancer and other specific cancers.
Comment & Response
Coronary In-Stent Restenosis Treated With Pacl*taxel-Coated Balloon vs Uncoated Balloon
AllisonKratka,MD; Rita F.Redberg,MD, MSc
Abstract Full Text
JAMA. 2024;332(2):169. doi:10.1001/jama.2024.9520
Coronary In-Stent Restenosis Treated With Pacl*taxel-Coated Balloon vs Uncoated Balloon—Reply
Robert W.Yeh,MD, MSc; Ajay J.Kirtane,MD, SM; AGENT IDE Investigators
Abstract Full Text
JAMA. 2024;332(2):169-170. doi:10.1001/jama.2024.9523
Preoperative GLP-1 Receptor Agonists and Risk of Postoperative Respiratory Complications
David A.Milder,BMedMD, BSc; Tamara Y.Milder,MBBS, MMed; PeterKam,MBBS, MD
Abstract Full Text
JAMA. 2024;332(2):170-171. doi:10.1001/jama.2024.10029
Preoperative GLP-1 Receptor Agonists and Risk of Postoperative Respiratory Complications
MarcLevi,MD
Abstract Full Text
JAMA. 2024;332(2):171. doi:10.1001/jama.2024.10023
Preoperative GLP-1 Receptor Agonists and Risk of Postoperative Respiratory Complications
Ion A.Hobai,MD, PhD
Abstract Full Text
JAMA. 2024;332(2):171-172. doi:10.1001/jama.2024.10026
Preoperative GLP-1 Receptor Agonists and Risk of Postoperative Respiratory Complications—Reply
Anjali A.Dixit,MD, MPH; Brian T.Bateman,MD, MS; Eric C.Sun,MD, PhD
Abstract Full Text
JAMA. 2024;332(2):172-173. doi:10.1001/jama.2024.10032
Correction
Errors in Table 2
Abstract Full Text
free access
JAMA. 2024;332(2):173. doi:10.1001/jama.2024.11152
Removal of Conflict of Interest Disclosure
Abstract Full Text
free access
JAMA. 2024;332(2):173. doi:10.1001/jama.2024.11869
JAMA Masthead
JAMA
Abstract Full Text
free access
JAMA. 2024;332(2):89-90. doi:10.1001/jama.2023.18338
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New Online
Treatment Approaches for Opioid Use Disorder Offered in US Substance Use Treatment Facilities
Research Letter | July 11, 2024
Smallpox Readiness: Modern Strategies Against an Ancient Disease
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Vitamin Confusion
JAMA Revisited | July 11, 2024
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